When you see all regional Pokemon you get access to a secret area with a shiny Haxorus.

Complete the National dex and you get an item that boosts shiny encounters.

Latias, Latios, Regirock, Regice, Registeel, Cresslia, Heatran.

Zoura for free.

The new forms are Zekrom/Reshiram combined with Kyurem using an item.

The new set of gyms are:
1)Cheren in Aspertia City
2)Roxie (Homika in Japan) in Virbank City
The order of the rest is unconfirmed at the moment...
Drayden in Opelucid City
Clay in Driftveil City
Elesa in Nimbasa City
Skyla in Mistralton City
Burgh in Castelia City
Marlon (Shizui in Japan)

Rival's English name (Named Hue in Japan) is Hugh.

Pokewood is called Pokestar Studios in the English release. It's in Virbank City. You'll be able to create movie premieres that will be shown at the in-game theater, where the audience gives it a rating based on script choices and battle sequences. You can even create sequels to existing movies. You'll have plenty of genres to choose from, from hilarious romantic comedies to awesome action movies to creepy horror movies.

Bianca is now Professor Juniper's assistant, with short hair and glasses.

For the first time, the Trainer School is in the starting town, Aspertia City, taught by Gym Leader Cheren.

When playing Black 2 and White 2 on 3DS, you can transfer Pokemon caught on the Pokemon Dream Radar application to your game.

The new forms of the Kami Trio (Tornadus, Thunderus, and Landorus) will be called their Therian Formes.

Keldeo's new forme is called the Resolution Forme.

Team Plasma returns! With a new plan to freeze the entire Unova Region!